I received a Ph.D. in Biochemistry from the University of Basel, Switzerland, in 1995 and then worked as a post-doctoral researcher at Cutaneous Biology Research Center at Massachusetts General Hospital in Boston, Massachusetts (USA). I am currently leading the Institute of Oral and Musculoskeletal Biology at the University of Cologne, Germany, and I am an External Collaborator within the Development and Evolutionary Morphogenesis group of cE3c, where I spent a 6 month sabbatical in 2014. I am a professor of Experimental Dentistry at the University of Cologne, Germany. My research focuses on the function of proteins of the extracellular matrix. These molecules are secreted by cells and form a network between cells, which provides tissue and organs with the necessary stability and elasticity. In addition to their structural function these proteins are needed for a large number of different developmental processes including skeletal muscle development and the proper connection of skeletal muscles to tendons and bones. My work within the DEM group focusses on the role of extracellular matrix proteins in the development of skeletal muscle.
Grandin, M., Meier, M., Delcros, J.G., Nikodemus, D., Reuten, R., Patel, T.R., Goldschneider, D., Orriss, G., Krahn, N., Boussouar, A., Abes, R., Dean, Y., Neves, D., Bernet, A., Depil, S., Schneiders, F., Poole, K., Dante, R., Koch, M., Mehlen, P. & Stetefeld, J. (2016) Structural decoding of the Netrin-1/UNC5 interaction and its therapeutical implications in cancers.Cancer Cell, 29(2), 173-185. DOI:10.1016/j.ccell.2016.01.001 (IF2016 27,407; Q1 Cell Biology)