Telephone 217500000 (ext.22332)
Andreia Marcelino Nunes is conducting a Ph.D. in Developmental Biology by the University of Lisbon starting in 2013 within the Development and Evolutionary Morphogenesis of cE3c. She is working on the project “Changing laminin niches in skeletal muscle: dissecting their role in development and disease” under the supervision of Prof. Sólveig Thorsteinsdóttir and Dr. Marianne Deries and in close collaboration with Prof. Dean J. Burkin at the University of Nevada, USA. In this Ph.D. project we aim to better understand the role of the extracellular matrix in myogenesis and study how defects in myofibre-extracellular matrix binding develops into muscular dystrophies.
Nunes, A.M., Wuebbles, R.D., Sarathy, A., Fontelonga, T.M., Deries, M., Burkin, D.J. & Thorsteinsdóttir, S. (2017) Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.Human Molecular Genetics, 26(11), 2018-2033. DOI:10.1093/hmg/ddx083 (IF2016 5,340; Q1 Biochemistry & Molecular Biology)
Silva, A.C., Rodrigues, S.C., Caldeira, J., Nunes, A.M., Sampaio-Pinto, V., Resende, T.P., Oliveira, M.J., Barbosa, M.A., Thorsteinsdóttir, S., Nascimento, D.S., Pinto-do-Ó, P. (2016) Three-dimensional scaffolds of fetal decellularized hearts exhibit enhanced potential to support cardiac cells in comparison to the adult.Biomaterials, 104, 52-64. DOI:10.1016/j.biomaterials.2016.06.062 (IF2016 8,402; Q1 Materials Science, Biomaterials)
Gomes de Almeida, P., Pinheiro, G., Nunes, A.M., Gonçalves, A.B. & Thorsteinsdóttir, S. (2016) Fibronectin assembly during early embryo development: a versatile communication system between cells and tissues.Developmental Dynamics, 245(4), 520-535. DOI:10.1002/dvdy.24391 (IF2016 2,004; Q1 Anatomy & Morphology)